According to court documents, Shameyer Ronnice Ashburn confessed to detectives that she choked her six-year-old son until he was dead.
Franklin Police say they responded to a room at the Days Inn motel at 1660 Armory Drive in regards to an unresponsive child.
The child was transported to the emergency room at Southampton Memorial Hospital where he was pronounced dead.
During the investigation, detectives developed the boy's mother as a person of interest in his death.
Shameyer Ronnice Ashburn, 24, was charged with the murder. She was sent to the Western Tidewater Regional Jail where she is being held without bond.