The USS Kearsarge and USS San Antonio left Naval Station Norfolk Monday.
The ships, along with the USS Carter Hall, will now head down to Camp Lejeune in North Carolina to pick up marines before heading to the Middle East.
Family and friends were lined up today to get in their last goodbyes before the ship left.
The USS Carter Hall left from JEB Little Creek Fort Story Monday.
There's no word yet on how long the amphibious ready group will be deployed.